-----BEGIN PRIVACY-ENHANCED MESSAGE----- Proc-Type: 2001,MIC-CLEAR Originator-Name: webmaster@www.sec.gov Originator-Key-Asymmetric: MFgwCgYEVQgBAQICAf8DSgAwRwJAW2sNKK9AVtBzYZmr6aGjlWyK3XmZv3dTINen TWSM7vrzLADbmYQaionwg5sDW3P6oaM5D3tdezXMm7z1T+B+twIDAQAB MIC-Info: RSA-MD5,RSA, LHkStf1qkWmiDHE4QxC8gzBbBLkAa24svmjNMNi/PAnBr3wrIYjYjio1cFdpE5Ba nNtmiLMwDt4ZfzzVjQvMrg== 0000950142-03-000921.txt : 20030521 0000950142-03-000921.hdr.sgml : 20030521 20030521161302 ACCESSION NUMBER: 0000950142-03-000921 CONFORMED SUBMISSION TYPE: SC 13G/A PUBLIC DOCUMENT COUNT: 4 FILED AS OF DATE: 20030521 GROUP MEMBERS: FRANK H. PEARL GROUP MEMBERS: GEORGE SOROS GROUP MEMBERS: PERSEUS BIOTECH FUND PARTNERS, LLC GROUP MEMBERS: PERSEUS EC, LLC GROUP MEMBERS: PERSEUS-SOROS BIOPHARMACEUTICAL FUND, LP GROUP MEMBERS: PERSEUS-SOROS PARTNERS, LLC GROUP MEMBERS: PERSEUSPUR, LLC GROUP MEMBERS: SFM AH, LLC GROUP MEMBERS: SFM PARTICIPATION, LP GROUP MEMBERS: SOROS FUND MANAGEMENT LLC SUBJECT COMPANY: COMPANY DATA: COMPANY CONFORMED NAME: COLLAGENEX PHARMACEUTICALS INC CENTRAL INDEX KEY: 0001012270 STANDARD INDUSTRIAL CLASSIFICATION: PHARMACEUTICAL PREPARATIONS [2834] IRS NUMBER: 521758016 STATE OF INCORPORATION: DE FISCAL YEAR END: 1231 FILING VALUES: FORM TYPE: SC 13G/A SEC ACT: 1934 Act SEC FILE NUMBER: 005-47825 FILM NUMBER: 03714685 BUSINESS ADDRESS: STREET 1: 41 UNIVERSITY DRIVE CITY: NEWTON STATE: PA ZIP: 18940 BUSINESS PHONE: 2155797388 MAIL ADDRESS: STREET 1: 41 UNIVERSITY DRIVE CITY: NEWTON STATE: PA ZIP: 18940 FILED BY: COMPANY DATA: COMPANY CONFORMED NAME: SOROS GEORGE CENTRAL INDEX KEY: 0000900203 STANDARD INDUSTRIAL CLASSIFICATION: UNKNOWN SIC - 0000 [0000] STATE OF INCORPORATION: NY FISCAL YEAR END: 1231 FILING VALUES: FORM TYPE: SC 13G/A BUSINESS ADDRESS: STREET 1: 888 SEVENTH AVENUE STREET 2: 33RD FLOOR CITY: NEW YORK STATE: NY ZIP: 10106 BUSINESS PHONE: 212-262--6 MAIL ADDRESS: STREET 1: 888 SEVENTH AVE STREET 2: 33RD FLR CITY: NEW YORK STATE: NY ZIP: 10106 SC 13G/A 1 sc13ga1-collagenex.txt AMENDMENT NO. 1 UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 (Amendment No. 1)* COLLAGENEX PHARMACEUTICALS, INC. (Name of Issuer) COMMON STOCK, PAR VALUE $.01 PER SHARE (Title of Class of Securities) 19419B100 (CUSIP Number) MAY 12, 2003 (Date of Event Which Requires Filing of this Statement) Check the appropriate box to designate the rule pursuant to which this Schedule is filed: [_] Rule 13d-1(b) [X] Rule 13d-1(c) [_] Rule 13d-1(d) *The remainder of this cover page shall be filled out for a reporting person's initial filing on this form with respect to the subject class of securities, and for any subsequent amendment containing information which would alter disclosures provided in a prior cover page. The information required on the reminder of this cover page shall not be deemed to be "filed" for the purpose of Section 18 of the Securities Exchange Act of 1934 ("Act") or otherwise subject to the liabilities of that section of the Act but shall be subject to all other provisions of the Act (however, see the Notes). CUSIP NO. 19419B100 Schedule 13G Page 2 of 24 - -------------------------------------------------------------------------------- 1. Name of Reporting Person Perseus-Soros BioPharmaceutical Fund, LP S.S. or I.R.S. Identifica- tion No.of Above Person - -------------------------------------------------------------------------------- 2. Check the Appropriate Box (a) [_] if a Member of a Group (b) [X] - -------------------------------------------------------------------------------- 3. S.E.C. Use Only - -------------------------------------------------------------------------------- 4. Citizenship or Place of Organization Delaware - -------------------------------------------------------------------------------- Number of Shares (5) Sole Voting Power 900,888 (1) ------------- Beneficially (6) Shared Voting Power 0 ------------- Owned by Each (7) Sole Dispositive Power 900,888 (1) ------------- Reporting Person (8) Shared Dispositive Power 0 ------------- - -------------------------------------------------------------------------------- 9. Aggregate Amount Beneficially Owned by Each Reporting Person 900,888 (1) - -------------------------------------------------------------------------------- 10. Check if the Aggregate Amount in Row (9) Excludes Certain Shares [X] - -------------------------------------------------------------------------------- 11. Percent of Class Represented by Amount in Row 9 7.72% ------------- - -------------------------------------------------------------------------------- 12. Type of Reporting Person PN - -------------------------------------------------------------------------------- - ------------------------ 1 Includes warrants to purchase 266,668 shares of Common Stock. CUSIP NO. 19419B100 Schedule 13G Page 3 of 24 - -------------------------------------------------------------------------------- 1. Name of Reporting Person Perseus-Soros Partners, LLC S.S. or I.R.S. Identifica- tion No.of Above Person - -------------------------------------------------------------------------------- 2. Check the Appropriate Box (a) [_] if a Member of a Group (b) [X] - -------------------------------------------------------------------------------- 3. S.E.C. Use Only - -------------------------------------------------------------------------------- 4. Citizenship or Place of Organization Delaware - -------------------------------------------------------------------------------- Number of Shares (5) Sole Voting Power 900,888 (1) ------------- Beneficially (6) Shared Voting Power 0 ------------- Owned by Each (7) Sole Dispositive Power 900,888 (1) ------------- Reporting Person (8) Shared Dispositive Power 0 ------------- - -------------------------------------------------------------------------------- 9. Aggregate Amount Beneficially Owned by Each Reporting Person 900,888 (1) - -------------------------------------------------------------------------------- 10. Check if the Aggregate Amount in Row (9) Excludes Certain Shares [X] - -------------------------------------------------------------------------------- 11. Percent of Class Represented by Amount in Row 9 7.72% ------------- - -------------------------------------------------------------------------------- 12. Type of Reporting Person OO - -------------------------------------------------------------------------------- - ------------------------ 1 Includes warrants to purchase 266,668 shares of Common Stock. CUSIP NO. 19419B100 Schedule 13G Page 4 of 24 - -------------------------------------------------------------------------------- 1. Name of Reporting Person Perseus BioTech Fund Partners, LLC S.S. or I.R.S. Identifica- tion No.of Above Person - -------------------------------------------------------------------------------- 2. Check the Appropriate Box (a) [_] if a Member of a Group (b) [X] - -------------------------------------------------------------------------------- 3. S.E.C. Use Only - -------------------------------------------------------------------------------- 4. Citizenship or Place of Organization Delaware - -------------------------------------------------------------------------------- Number of Shares (5) Sole Voting Power 0 ------------- Beneficially (6) Shared Voting Power 900,888 (1) ------------- Owned by Each (7) Sole Dispositive Power 0 ------------- Reporting Person (8) Shared Dispositive Power 900,888 (1) ------------- - -------------------------------------------------------------------------------- 9. Aggregate Amount Beneficially Owned by Each Reporting Person 900,888 (1) - -------------------------------------------------------------------------------- 10. Check if the Aggregate Amount in Row (9) Excludes Certain Shares [X] - -------------------------------------------------------------------------------- 11. Percent of Class Represented by Amount in Row 9 7.72% ------------- - -------------------------------------------------------------------------------- 12. Type of Reporting Person OO - -------------------------------------------------------------------------------- - ------------------------ 1 Includes warrants to purchase 266,668 shares of Common Stock. CUSIP NO. 19419B100 Schedule 13G Page 5 of 24 - -------------------------------------------------------------------------------- 1. Name of Reporting Person SFM Participation, LP S.S. or I.R.S. Identifica- tion No.of Above Person - -------------------------------------------------------------------------------- 2. Check the Appropriate Box (a) [_] if a Member of a Group (b) [X] - -------------------------------------------------------------------------------- 3. S.E.C. Use Only - -------------------------------------------------------------------------------- 4. Citizenship or Place of Organization Delaware - -------------------------------------------------------------------------------- Number of Shares (5) Sole Voting Power 0 ------------- Beneficially (6) Shared Voting Power 900,888 (1) ------------- Owned by Each (7) Sole Dispositive Power 0 ------------- Reporting Person (8) Shared Dispositive Power 900,888 (1) ------------- - -------------------------------------------------------------------------------- 9. Aggregate Amount Beneficially Owned by Each Reporting Person 900,888 (1) - -------------------------------------------------------------------------------- 10. Check if the Aggregate Amount in Row (9) Excludes Certain Shares [X] - -------------------------------------------------------------------------------- 11. Percent of Class Represented by Amount in Row 9 7.72% ------------- - -------------------------------------------------------------------------------- 12. Type of Reporting Person PN - -------------------------------------------------------------------------------- - ------------------------ 1 Includes warrants to purchase 266,668 shares of Common Stock. CUSIP NO. 19419B100 Schedule 13G Page 6 of 24 - -------------------------------------------------------------------------------- 1. Name of Reporting Person SFM AH, LLC S.S. or I.R.S. Identifica- tion No.of Above Person - -------------------------------------------------------------------------------- 2. Check the Appropriate Box (a) [_] if a Member of a Group (b) [X] - -------------------------------------------------------------------------------- 3. S.E.C. Use Only - -------------------------------------------------------------------------------- 4. Citizenship or Place of Organization Delaware - -------------------------------------------------------------------------------- Number of Shares (5) Sole Voting Power 0 ------------- Beneficially (6) Shared Voting Power 900,888 (1) ------------- Owned by Each (7) Sole Dispositive Power 0 ------------- Reporting Person (8) Shared Dispositive Power 900,888 (1) ------------- - -------------------------------------------------------------------------------- 9. Aggregate Amount Beneficially Owned by Each Reporting Person 900,888 (1) - -------------------------------------------------------------------------------- 10. Check if the Aggregate Amount in Row (9) Excludes Certain Shares [X] - -------------------------------------------------------------------------------- 11. Percent of Class Represented by Amount in Row 9 7.72% ------------- - -------------------------------------------------------------------------------- 12. Type of Reporting Person OO - -------------------------------------------------------------------------------- - ------------------------ 1 Includes warrants to purchase 266,668 shares of Common Stock. CUSIP NO. 19419B100 Schedule 13G Page 7 of 24 - -------------------------------------------------------------------------------- 1. Name of Reporting Person Perseus EC, LLC S.S. or I.R.S. Identifica- tion No.of Above Person - -------------------------------------------------------------------------------- 2. Check the Appropriate Box (a) [_] if a Member of a Group (b) [X] - -------------------------------------------------------------------------------- 3. S.E.C. Use Only - -------------------------------------------------------------------------------- 4. Citizenship or Place of Organization Delaware - -------------------------------------------------------------------------------- Number of Shares (5) Sole Voting Power 0 ------------- Beneficially (6) Shared Voting Power 900,888 (1) ------------- Owned by Each (7) Sole Dispositive Power 0 ------------- Reporting Person (8) Shared Dispositive Power 900,888 (1) ------------- - -------------------------------------------------------------------------------- 9. Aggregate Amount Beneficially Owned by Each Reporting Person 900,888 (1) - -------------------------------------------------------------------------------- 10. Check if the Aggregate Amount in Row (9) Excludes Certain Shares [X] - -------------------------------------------------------------------------------- 11. Percent of Class Represented by Amount in Row 9 7.72% ------------- - -------------------------------------------------------------------------------- 12. Type of Reporting Person OO - -------------------------------------------------------------------------------- - ------------------------ 1 Includes warrants to purchase 266,668 shares of Common Stock. CUSIP NO. 19419B100 Schedule 13G Page 8 of 24 - -------------------------------------------------------------------------------- 1. Name of Reporting Person Perseuspur, LLC S.S. or I.R.S. Identifica- tion No.of Above Person - -------------------------------------------------------------------------------- 2. Check the Appropriate Box (a) [_] if a Member of a Group (b) [X] - -------------------------------------------------------------------------------- 3. S.E.C. Use Only - -------------------------------------------------------------------------------- 4. Citizenship or Place of Organization Delaware - -------------------------------------------------------------------------------- Number of Shares (5) Sole Voting Power 0 ------------- Beneficially (6) Shared Voting Power 900,888 (1) ------------- Owned by Each (7) Sole Dispositive Power 0 ------------- Reporting Person (8) Shared Dispositive Power 900,888 (1) ------------- - -------------------------------------------------------------------------------- 9. Aggregate Amount Beneficially Owned by Each Reporting Person 900,888 (1) - -------------------------------------------------------------------------------- 10. Check if the Aggregate Amount in Row (9) Excludes Certain Shares [X] - -------------------------------------------------------------------------------- 11. Percent of Class Represented by Amount in Row 9 7.72% ------------- - -------------------------------------------------------------------------------- 12. Type of Reporting Person OO - -------------------------------------------------------------------------------- - ------------------------ 1 Includes warrants to purchase 266,668 shares of Common Stock. CUSIP NO. 19419B100 Schedule 13G Page 9 of 24 - -------------------------------------------------------------------------------- 1. Name of Reporting Person Frank H. Pearl S.S. or I.R.S. Identifica- (in the capacity described herein) tion No.of Above Person - -------------------------------------------------------------------------------- 2. Check the Appropriate Box (a) [_] if a Member of a Group (b) [X] - -------------------------------------------------------------------------------- 3. S.E.C. Use Only - -------------------------------------------------------------------------------- 4. Citizenship or Place of Organization United States - -------------------------------------------------------------------------------- Number of Shares (5) Sole Voting Power 0 ------------- Beneficially (6) Shared Voting Power 1,049,468 (1)(2) ------------- Owned by Each (7) Sole Dispositive Power 0 ------------- Reporting Person (8) Shared Dispositive Power 1,049,468 (1)(2) ------------- - -------------------------------------------------------------------------------- 9. Aggregate Amount Beneficially Owned by Each Reporting Person 1,049,468 (1)(2) - -------------------------------------------------------------------------------- 10. Check if the Aggregate Amount in Row (9) Excludes Certain Shares [_] - -------------------------------------------------------------------------------- 11. Percent of Class Represented by Amount in Row 9 8.99% ------------- - -------------------------------------------------------------------------------- 12. Type of Reporting Person IN - -------------------------------------------------------------------------------- - ------------------------ 1 Includes warrants to purchase 266,668 shares of Common Stock. 2 See Item 4(a) herein. CUSIP NO. 19419B100 Schedule 13G Page 10 of 24 - -------------------------------------------------------------------------------- 1. Name of Reporting Person Soros Fund Management LLC S.S. or I.R.S. Identifica- tion No.of Above Person - -------------------------------------------------------------------------------- 2. Check the Appropriate Box (a) [_] if a Member of a Group (b) [X] - -------------------------------------------------------------------------------- 3. S.E.C. Use Only - -------------------------------------------------------------------------------- 4. Citizenship or Place of Organization Delaware - -------------------------------------------------------------------------------- Number of Shares (5) Sole Voting Power 0 ------------- Beneficially (6) Shared Voting Power 900,888 (1) ------------- Owned by Each (7) Sole Dispositive Power 0 ------------- Reporting Person (8) Shared Dispositive Power 900,888 (1) ------------- - -------------------------------------------------------------------------------- 9. Aggregate Amount Beneficially Owned by Each Reporting Person 900,888 (1) - -------------------------------------------------------------------------------- 10. Check if the Aggregate Amount in Row (9) Excludes Certain Shares [X] - -------------------------------------------------------------------------------- 11. Percent of Class Represented by Amount in Row 9 7.72% ------------- - -------------------------------------------------------------------------------- 12. Type of Reporting Person OO; IA - -------------------------------------------------------------------------------- - ------------------------ 1 Includes warrants to purchase 266,668 shares of Common Stock. CUSIP NO. 19419B100 Schedule 13G Page 11 of 24 - -------------------------------------------------------------------------------- 1. Name of Reporting Person George Soros S.S. or I.R.S. Identifica- (in the capacity described herein) tion No.of Above Person - -------------------------------------------------------------------------------- 2. Check the Appropriate Box (a) [_] if a Member of a Group (b) [X] - -------------------------------------------------------------------------------- 3. S.E.C. Use Only - -------------------------------------------------------------------------------- 4. Citizenship or Place of Organization United States - -------------------------------------------------------------------------------- Number of Shares (5) Sole Voting Power 0 ------------- Beneficially (6) Shared Voting Power 900,888 (1) ------------- Owned by Each (7) Sole Dispositive Power 0 ------------- Reporting Person (8) Shared Dispositive Power 900,888 (1) ------------- - -------------------------------------------------------------------------------- 9. Aggregate Amount Beneficially Owned by Each Reporting Person 900,888 (1) - -------------------------------------------------------------------------------- 10. Check if the Aggregate Amount in Row (9) Excludes Certain Shares [X] - -------------------------------------------------------------------------------- 11. Percent of Class Represented by Amount in Row 9 7.72% ------------- - -------------------------------------------------------------------------------- 12. Type of Reporting Person IA - -------------------------------------------------------------------------------- - ------------------------ 1 Includes warrants to purchase 266,668 shares of Common Stock. CUSIP NO. 19419B100 Schedule 13G Page 12 of 24 Item 1. (a) NAME OF ISSUER CollaGenex Pharmaceuticals, Inc. (the "Company") (b) ADDRESS OF ISSUER'S PRINCIPAL EXECUTIVE OFFICES 41 University Drive Newtown, PA 18940 Item 2. (a) NAMES OF PERSONS FILING (i) Perseus-Soros BioPharmaceutical Fund, LP, a Delaware limited partnership ("PSBF"); (ii) Perseus-Soros Partners, LLC, a Delaware limited liability company ("PSP GP" and general partner of PSBF); (iii) Perseus BioTech Fund Partners, LLC, a Delaware limited liability company ("PBFP Partners" and a managing member of PSP GP); (iv) SFM Participation, LP, a Delaware limited partnership ("SFM Participation" and a managing member of PSP GP); (v) SFM AH, LLC, a Delaware limited liability company ("SFM AH" and general partner of SFM Participation); (vi) Perseus EC, LLC, a Delaware limited liability company ("Perseus EC" and managing member of PBFP Partners); (vii) Perseuspur, LLC, a Delaware limited liability company ("Perseuspur" and member of Perseus EC); (viii) Mr. Frank H. Pearl ("Mr. Pearl" and sole member of Perseuspur); (ix) Soros Fund Management LLC, a Delaware limited liability company ("SFM LLC"); and (x) Mr. George Soros ("Mr. Soros" and Chairman of SFM LLC). (b) ADDRESS OF PRINCIPAL BUSINESS OFFICE The address of the principal business offices of (i) PSBF and (ii) PSP GP is 888 Seventh Avenue, 29th Floor, New York, NY 10106. The address of the principal business offices of (i) PBFP Partners, (ii) Perseus EC, (iii) Perseuspur and (iv) Mr. Pearl is 2099 Pennsylvania Ave., N.W., Suite 900, Washington, D.C. 20006. The address of the principal business offices of (i) SFM Participation, (ii) SFM AH, (iii) SFM LLC and (iv) Mr. Soros is 888 Seventh Avenue, 33rd Floor, New York, NY 10106. (c) CITIZENSHIP PSBF - a Delaware limited partnership CUSIP NO. 19419B100 Schedule 13G Page 13 of 24 PSP GP - a Delaware limited liability company PBFP Partners - a Delaware limited liability company SFM Participation - a Delaware limited partnership SFM AH - a Delaware limited liability company Perseus EC - a Delaware limited liability company Perseuspur - a Delaware limited liability company Mr. Pearl - United States SFM LLC - a Delaware limited liability company Mr. Soros - United States (d) TITLE OF CLASS OF SECURITIES Common Stock, par value $.01 per share (the "Common Stock" or "Shares") (e) CUSIP NUMBER 19419B100 Information contained herein concerning SFM Participation, SFM AH, Mr. Soros and SFM LLC has been provided by SFM LLC. PSBF, PSP GP, PBFP Partners, Perseus EC, Perseuspur and Mr. Pearl assume no responsibility for such information. Information contained herein concerning PBFP Partners, Perseus EC, Perseuspur and Mr. Pearl has been provided by each such Reporting Person. PSBF, PSP GP, SFM Participation, SFM AH, Mr. Soros and SFM LLC assume no responsibility for such information. Item 3. This statement is not filed pursuant to either Rule 13d-1(b) or 13d-2(b) or (c). Item 4. OWNERSHIP. (a) AMOUNT BENEFICIALLY OWNED: Each of the Reporting Persons, other than Mr. Pearl, may be deemed to beneficially own an aggregate of 900,888 shares of Common Stock. Mr. Pearl may be deemed to beneficially own an aggregate of 1,049,468 shares of Common Stock as a result of his voting and dispositive power over the 900,888 shares of Common Stock owned by PSBF and an additional 148,580 shares of Common Stock beneficially owned by New York Life BioVenture Partners LLC, a Delaware limited liability company ("New York Life"). New York Life may be deemed to be an affiliate of Mr. Pearl. (b) PERCENTAGE OWNED: Based on calculations made in accordance with Rule 13d-3(d), and there being 11,409,641 shares of Common Stock outstanding as of this date, each of the Reporting Persons, other than Mr. Pearl, may be deemed to beneficially own approximately 7.72% of the outstanding CUSIP NO. 19419B100 Schedule 13G Page 14 of 24 shares of Common Stock on a diluted basis in accordance with Rule 13d-3(d). Based on calculations made in accordance with Rule 13d-3(d), and there being 11,409,641 shares of Common Stock outstanding as of this date, Mr. Pearl may be deemed to beneficially own approximately 8.99% of the outstanding shares of Common Stock on a diluted basis in accordance with Rule 13d-3(d). (c) NUMBER OF SHARES AS TO WHICH SUCH PERSON HAS: (i) Each of PSBF and PSP GP may be deemed to have sole power to direct the voting and disposition of the 900,888 shares of Common Stock beneficially owned by PSBF. (ii) By virtue of the relationships between and among the Reporting Persons as described in Item 2, each of the Reporting Persons, other than PSBF, PSP GP and Mr. Pearl, may be deemed to share the power to direct the voting and disposition of the 900,888 shares of Common Stock beneficially owned by PSBF. Mr. Pearl may be deemed to share the power to direct the voting and disposition of the 900,888 shares of Common Stock beneficially owned by PSBF and the 148,580 shares of Common Stock beneficially owned by New York Life. PSBF, PSP GP, PBFP Partners, Perseus EC, Perseuspur, SFM Participation, SFM AH, Mr. Soros and SFM LLC disclaim beneficial ownership of the 148,580 shares of Common Stock beneficially owned by New York Life. Item 5. OWNERSHIP OF FIVE PERCENT OR LESS OF A CLASS Not applicable. Item 6. OWNERSHIP OF MORE THAN FIVE PERCENT ON BEHALF OF ANOTHER PERSON The partners of PSBF have the right to participate in the receipt of dividends from, or proceeds from the sale of, the securities held for the account of PSBF in accordance with their ownership interests in PSBF. Item 7. IDENTIFICATION AND CLASSIFICATION OF SUBSIDIARY WHICH ACQUIRED THE SECURITY BEING REPORTED ON BY THE PARENT HOLDING COMPANY Not applicable. Item 8. IDENTIFICATION AND CLASSIFICATION OF MEMBERS OF THE GROUP Not applicable. Item 9. NOTICE OF DISSOLUTION OF GROUP Not applicable. CUSIP NO. 19419B100 Schedule 13G Page 15 of 24 Item 10. CERTIFICATION By signing below we certify that, to the best of our knowledge and belief, the securities referred to above were not acquired and are not held for the purpose of or with the effect of changing or influencing the control of the issuer of the securities and were not acquired and are not held in connection with or as a participant in any transaction having that purpose or effect. [REMAINDER OF PAGE INTENTIONALLY LEFT BLANK] CUSIP NO. 19419B100 Schedule 13G Page 16 of 24 SIGNATURES After reasonable inquiry and to the best of our knowledge and belief, the undersigned certify that the information set forth in this statement is true, complete and correct. Dated as of May 21, 2003 PERSEUS-SOROS BIOPHARMACEUTICAL FUND, LP By: Perseus-Soros Partners, LLC, Its General Partner By: SFM Participation, L.P., Its Managing Member By: SFM AH, LLC, Its General Partner By: Soros Private Funds Management LLC, Its Managing Member /s/ Jodye Anzalotta ---------------------------------------------------- By: Jodye Anzalotta Title: Attorney-in-Fact PERSEUS-SOROS PARTNERS, LLC By: SFM Participation, L.P., Its Managing Member By: SFM AH, LLC, Its General Partner By: Soros Private Funds Management LLC, Its Managing Member /s/ Jodye Anzalotta ---------------------------------------------------- By: Jodye Anzalotta Title: Attorney-in-Fact CUSIP NO. 19419B100 Schedule 13G Page 17 of 24 PERSEUS BIOTECH FUND PARTNERS, LLC By: Perseuspur EC, L.L.C., Managing Member By: Perseuspur, LLC, Member /s/ Rodd Macklin ---------------------------------------------------- By: Rodd Macklin Title: Secretary and Treasurer PERSEUS EC, L.L.C. By: Perseuspur, LLC, Member /s/ Rodd Macklin ---------------------------------------------------- By: Rodd Macklin Title: Secretary and Treasurer PERSEUSPUR, LLC /s/ Rodd Macklin ---------------------------------------------------- By: Rodd Macklin Title: Secretary and Treasurer MR. FRANK H. PEARL /s/ Rodd Macklin ---------------------------------------------------- By: Rodd Macklin Title: Attorney-in-Fact CUSIP NO. 19419B100 Schedule 13G Page 18 of 24 SFM PARTICIPATION, LP By: SFM AH, LLC, Its General Partner By: Soros Private Funds Management LLC, Its Managing Member /s/ Jodye Anzalotta ---------------------------------------------------- By: Jodye Anzalotta Title: Attorney-in-Fact SFM AH, LLC By: Soros Private Funds Management LLC, Its Managing Member /s/ Jodye Anzalotta ---------------------------------------------------- By: Jodye Anzalotta Title: Attorney-in-Fact SOROS FUND MANAGEMENT LLC /s/ Jodye Anzalotta ---------------------------------------------------- By: Jodye Anzalotta Title: Assistant Counsel MR. GEORGE SOROS /s/ Jodye Anzalotta ---------------------------------------------------- By: Jodye Anzalotta Title: Attorney-in-Fact CUSIP NO. 19419B100 Schedule 13G Page 19 of 24 EXHIBIT INDEX Exhibit 1. Joint Filing Agreement as required by Rule 13d-1(k)(1) under the Securities Exchange Act of 1934, as amended. Exhibit 2. Power of Attorney dated October 30, 2002 appointing each of Armando T. Belly, Jodye Anzalotta, John F. Brown, Maryann Canfield, Richard D. Holahan, Jr. and Robert Soros as Attorney-In-Fact for George Soros. Exhibit 3. Power of Attorney dated April 9, 2003 appointing Rodd Macklin as Attorney-In-Fact for Frank H. Pearl. EX-99 3 ex1_sc13ga1-collagenex.txt EXHIBIT 1 CUSIP NO. 19419B100 Schedule 13G Page 20 of 24 EXHIBIT 1 --------- JOINT FILING AGREEMENT PURSUANT TO RULE 13d-1(k)(1) The undersigned acknowledge and agree that the foregoing statement on Schedule 13G is filed on behalf of each of the undersigned and that all subsequent amendments to this statement on Schedule 13G shall be filed on behalf of each of the undersigned without the necessity of filing additional joint filing statements. The undersigned acknowledge that each shall be responsible for the timely filing of such amendments, and for the completeness and accuracy of the information concerning him, her or it contained herein, but shall not be responsible for the completeness and accuracy of the information concerning the other entities or persons, except to the extent that he, she or it knows or has reason to believe that such information is inaccurate. Dated as of May 21, 2003 PERSEUS-SOROS BIOPHARMACEUTICAL FUND, LP By: Perseus-Soros Partners, LLC, Its General Partner By: SFM Participation, L.P., Its Managing Member By: SFM AH, LLC, Its General Partner By: Soros Private Funds Management LLC, Its Managing Member /s/ Jodye Anzalotta ---------------------------------------------------- By: Jodye Anzalotta Title: Attorney-in-Fact PERSEUS-SOROS PARTNERS, LLC By: SFM Participation, L.P., Its Managing Member By: SFM AH, LLC, Its General Partner By: Soros Private Funds Management LLC, Its Managing Member /s/ Jodye Anzalotta ---------------------------------------------------- By: Jodye Anzalotta Title: Attorney-in-Fact CUSIP NO. 19419B100 Schedule 13G Page 21 of 24 PERSEUS BIOTECH FUND PARTNERS, LLC By: Perseuspur EC, L.L.C., Managing Member By: Perseuspur, LLC, Member /s/ Rodd Macklin ---------------------------------------------------- By: Rodd Macklin Title: Secretary and Treasurer PERSEUS EC, L.L.C. By: Perseuspur, LLC, Member /s/ Rodd Macklin ---------------------------------------------------- By: Rodd Macklin Title: Secretary and Treasurer PERSEUSPUR, LLC /s/ Rodd Macklin ---------------------------------------------------- By: Rodd Macklin Title: Secretary and Treasurer MR. FRANK H. PEARL /s/ Rodd Macklin ---------------------------------------------------- By: Rodd Macklin Title: Attorney-in-Fact CUSIP NO. 19419B100 Schedule 13G Page 22 of 24 SFM PARTICIPATION, LP By: SFM AH, LLC, Its General Partner By: Soros Private Funds Management LLC, Its Managing Member /s/ Jodye Anzalotta ---------------------------------------------------- By: Jodye Anzalotta Title: Attorney-in-Fact SFM AH, LLC By: Soros Private Funds Management LLC, Its Managing Member /s/ Jodye Anzalotta ---------------------------------------------------- By: Jodye Anzalotta Title: Attorney-in-Fact SOROS FUND MANAGEMENT LLC /s/ Jodye Anzalotta ---------------------------------------------------- By: Jodye Anzalotta Title: Assistant Counsel MR. GEORGE SOROS /s/ Jodye Anzalotta ---------------------------------------------------- By: Jodye Anzalotta Title: Attorney-in-Fact EX-24 4 ex2_sc13ga1-collagenex.txt EXHIBIT 2 CUSIP NO. 19419B100 Schedule 13G Page 23 of 24 EXHIBIT 2 --------- POWER OF ATTORNEY KNOW ALL MEN BY THESE PRESENT, that I, GEORGE SOROS, hereby make, constitute and appoint each of ARMANDO T. BELLY, JODYE ANZALOTTA, JOHN F. BROWN, MARYANN CANFIELD, RICHARD D. HOLAHAN, JR. and ROBERT SOROS acting individually, as my agent and attorney-in-fact for the purpose of executing in my name, (a) in my personal capacity or (b) in my capacity as Chairman of, member of or in other capacities with Soros Fund Management LLC ("SFM LLC") and each of its affiliates or entities advised by me or SFM LLC, all documents, certificates, instruments, statements, filings and agreements ("documents") to be filed with or delivered to any foreign or domestic governmental or regulatory body or required or requested by any other person or entity pursuant to any legal or regulatory requirement relating to the acquisition, ownership, management or disposition of securities, futures contracts or other investments, and any other documents relating or ancillary thereto, including without limitation all documents relating to filings with the Commodities Futures Trading Commission and National Futures Association, the United States Securities and Exchange Commission (the "SEC") pursuant to the Commodities Exchange Act and the Securities Act of 1933 or the Securities Exchange Act of 1934 (the "Act") and the rules and regulations promulgated thereunder, including all documents relating to the beneficial ownership of securities required to be filed with the SEC pursuant to Section 13(d) or Section 16(a) of the Act and any information statements on Form 13F required to be filed with the SEC pursuant to Section 13(f) of the Act. All past acts of the attorney-in-fact in furtherance of the foregoing are hereby ratified and confirmed. Execution of this power of attorney revokes that certain Power of Attorney dated as of the 15th day of January 2002 with respect to the same matters addressed above. This power of attorney shall be valid from the date hereof until revoked by me. IN WITNESS WHEREOF, I have executed this instrument as of the 30th day of October 2002. /s/ George Soros --------------------------------------- GEORGE SOROS EX-24 5 ex3_sc13ga1-collagenex.txt EXHIBIT 3 CUSIP NO. 19419B100 Schedule 13G Page 24 of 24 EXHIBIT 3 --------- POWER OF ATTORNEY KNOW ALL BY THESE PRESENTS, that I, FRANK H. PEARL, hereby make, constitute and appoint RODD MACKLIN as my agent and attorney-in-fact for the purpose of executing in my name, (a) in my personal capacity or (b) in my capacity as Chairman of, member of or in other capacities with Perseus LLC ("Perseus") and each of its affiliates or entities advised by me or Perseus, all documents, certificates, instruments, statements, filings and agreements ("documents") to be filed with or delivered to any foreign or domestic governmental or regulatory body or required or requested by any other person or entity pursuant to any legal or regulatory requirement relating to the acquisition, ownership, management or disposition of securities, futures contracts, or other investments, and any other documents relating or ancillary thereto, including but not limited to, all documents relating to filings with the Commodities Futures Trading Commission and National Futures Association, the United States Securities and Exchange Commission (the "SEC") pursuant to the Commodities Exchange Act and the Securities Act of 1933 or the Securities Exchange Act of 1934 (the "Act") and the rules and regulations promulgated thereunder, including all documents relating to the beneficial ownership of securities required to be filed with the SEC pursuant to Section 13(d) or Section 16(a) of the Act and information statements on Form 13F required to be filed with the SEC pursuant to Section 13(f) of the Act. All past acts of the attorney-in-fact in furtherance of the foregoing are hereby ratified and confirmed. This power of attorney shall be valid from the date hereof until revoked by me. IN WITNESS WHEREOF, I have executed this instrument as of the 9th day of April, 2003. /s/ Frank H. Pearl --------------------------------------- FRANK H. PEARL -----END PRIVACY-ENHANCED MESSAGE-----